Cut the chicken tenders into bite-sized pieces.
In a large bowl, whisk together the flour, cornstarch, garlic powder, paprika, chili powder, cayenne pepper, salt, and pepper until well combined.
Place the chicken pieces in the bowl with the dry rub and toss until evenly coated.
In a small saucepan, heat the hot sauce and pickle juice over medium heat until simmering.
Heat the vegetable oil in a large skillet over medium-high heat. Carefully add the chicken pieces in batches and fry until golden brown and cooked through, about 5 minutes per batch.
Transfer the cooked chicken to a bowl with the hot sauce mixture. Toss gently to coat the chicken evenly.
Serve the hot tenders immediately with your favorite dipping sauces, such as blue cheese or ranch dressing.